Journal of Vascular Surgery

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RS11. The Neoaortoiliac System Procedure for Aortic Infections: Long-Term Outcomes From a Large Single-Center Experience

June 1, 2018 - 00:00
Although challenging for the patients and surgical teams, the neoaortoiliac system (NAIS) procedure is a recognized treatment option for primary and secondary aortic infections. However, evidence is limited regarding long-term follow-up limiting its widespread acceptance as the gold-standard treatment. The aim of this study is to define long-term outcomes of patients treated with a NAIS reconstruction and to identify variables associated with a negative outcome.

SS35. Perioperative Mortality and Morbidity After Revascularization for Acute Aortic Occlusion

June 1, 2018 - 00:00
Acute aortic occlusion (AAO) is a life-threatening event necessitating prompt revascularization to the pelvis and lower extremities. Owing to its uncommon nature, outcomes after revascularization for AAO are not well-characterized. Our aim was to describe the perioperative morbidity and mortality associated with revascularization and to identify the patients at highest risk.

SS34. A Contemporary, 7-Year Analysis of Vascular Injury From the War in Afghanistan

June 1, 2018 - 00:00
Vascular injury is a leading cause of death and disability in military and civilian trauma. While a previous interim study defined the distribution of vascular injury during the wars in Iraq and Afghanistan, a contemporary epidemiologic assessment has not been performed. The objective of this study is to provide a current analysis of vascular injury during the final seven years of the war in Afghanistan, including characterization of anatomic injury patterns, mechanisms of injury and methods of acute management.

RS10. Real-Time Ergonomic Issues in Vascular Surgeons: How We Are Hurting Ourselves While Operating

June 1, 2018 - 00:00
Recent data suggest that over 40% of surgeons have physical pain and disability related to operating. In addition, 6% of vascular surgeons (VS) reported having to stop operating owing to work-related pain, which adversely impacts the national shortage in vascular surgery. To quantify the risk of musculoskeletal disorders, a prospective study of VS postures was performed using objective measures.

SS32. Perspectives and Perceived Needs of the Contemporary Vascular Surgery Trainee: Results of the National Association of Program Directors in Vascular Surgery Trainee Survey

June 1, 2018 - 00:00
This study identifies contemporary issues in the integrated vascular surgery residency and fellowship programs with a focus on the motivators and professional development needs of trainees. The purpose is to investigate resident experiences with an emphasis on burn-out, quality of life, and specialty threats specialty to optimize future vascular surgery recruitment and retention.

RS09. The Fundamentals of Vascular Surgery: A 6-Year Review of the First U.S. Dedicated Vascular Simulation Course

June 1, 2018 - 00:00
Duty-hour restrictions, changing training paradigms, and diminishing open surgical case volumes have caused dramatic shifts in vascular trainees experience over the past decade. While simulation training has been advocated as an augment to resident training, the benefits of short 3- to 4-day courses are largely unknown. The goal of this study was to perform a 6-year review of the first simulation course established for vascular trainees in the United States.

RS08. Inadequate Proximal Seal Length Predicts Complications After Endovascular Repair of Acute Type B Aortic Dissection

June 1, 2018 - 00:00
To evaluate the effect of proximal seal length on outcomes after endovascular repair of acute Type B aortic dissection (aTBAD).

SS31. TEVAR With Stent Grafts Alone or With a Composite Device Design in Patients With Acute Type B Aortic Dissection in the Setting of Malperfusion

June 1, 2018 - 00:00
To compare short-term outcomes in patients who underwent endovascular repair with stent grafts alone or with a composite device design (stent grafts plus a bare metal aortic stent) for acute, type B aortic dissection in the setting of malperfusion.

SS30. Late Outcomes of Different Hypogastric Stent Grafts in Aortoiliac Endografting With Iliac Branch Device: The pELVIS Registry

June 1, 2018 - 00:00
To evaluate long-term results of self-expanding versus balloon-expandable hypogastric stent grafts in conjunction with iliac branch devices (IBD) for aortoiliac aneurysm (AAIA) repair, in a multicenter experience (pELVIS Registry).

SS29. Long-Term Advantage of Iliac Branch Devices over Flared Limbs in the Treatment of Common Iliac Aneurysms

June 1, 2018 - 00:00
The endovascular treatment (EVAR) of abdominal aortic aneurysms (AAA) is often associated with the treatment of common iliac artery dilatation (CID). The treatment options for CID can be either flared limbs (FL) or iliac branch devices (IBD) in selected cases but their efficacy is still matter of debate. Aim of the present study was to evaluate the perioperative and long-term outcome of EVAR with FL or IBD for CID.

SS28. Long-Term Survival After Endovascular Repair and Open Repair in Patients With Anatomy Outside Endovascular Repair Indications for Use Criteria

June 1, 2018 - 00:00
Landmark randomized controlled trials comparing long-term survival outcomes for infrarenal abdominal aortic aneurysms (AAA) have compared open repair (OR) with endovascular repair (EVAR) in patients with suitable aortic anatomy. However, patients who do not meet indications for use (IFU) criteria are often still treated by EVAR even though some studies have shown higher graft-related adverse events. The goal of this study was to compare the long-term survival of EVAR and OR in patients with anatomy outside standard IFU criteria.

PC238. The Effect of Ischemia on Adipose-Derived Mesenchymal Stem Cells Expression In Vivo

June 1, 2018 - 00:00
Several animal models have demonstrated improvement in mesenchymal stem cells (MSCs) count and paracrine secretions under hypoxic conditions. We have demonstrated an increase in adipose derived mesenchymal stem cells (ADMSCs) count in ischemic compared with nonischemic tissues in a previous in vivo study. This follow-up study was performed to investigate the effect of critical limb ischemia, in a human model, on in-situ ADMSCs paracrine effects.

PC236. Cav-1 Regulates EphB4-Mediated Arteriovenous Fistula Maturation

June 1, 2018 - 00:00
Arteriovenous fistula (AVF) continues to be the most common access created for hemodialysis. However, many AVFs fail to mature, suggesting a need to improve AVF maturation. Caveolin1 (Cav-1) is the major scaffolding protein of caveolae, a distinct microdomain that serves as a flow-activated mechanosensor at the membrane of endothelial cells; Eph-B4 is the embryonic venous determinant. We have previously shown that Cav-1 is a mechanism of Eph-B4-mediated vessel remodeling in the murine vein graft model.

PC234. Ruptured Aortic Aneurysms and the Alternation of Biometeorologic Parameters: A New Method to Forecast Rare Events

June 1, 2018 - 00:00
The aim of our study was to examine the dependence of fatal outcome aortic aneurysm ruptures and alternation of complex meteorological patterns. Furthermore, with a new method we can measure the intensity of the connection and in case of a reliable meteorological forecast we can predict the occurrence of the events.

PC232. Metabolic Profiling of High-Risk Carotid Atherosclerosis

June 1, 2018 - 00:00
Stroke is a leading cause of death and disability worldwide. Approximately one quarter of all strokes are secondary to carotid atherosclerosis. There is a clinical need to improve risk stratification of carotid atherosclerosis, to better target surgical or interventional therapy and prevent stroke. This study aimed to determine diagnostic biomarkers of high-risk carotid atherosclerosis, and ensure the validity of such markers in the presence of alternative phenotypes of atherosclerotic disease.

PC230. Inhibition of Abdominal Aortic Aneurysm Expansion in a Preclinical Atherosclerotic LDLR-/- Minipig Model by miR-29b-Coated Balloon Angioplasty

June 1, 2018 - 00:00
Abdominal aortic aneurysm (AAA) is a major challenge in vascular surgery practice and apart from open surgery or endovascular stent implantation, no therapeutic option remains to clinicians. Micro-RNA 29b (miR-29b) has been shown to induce fibrosis in by interacting with vascular smooth muscle cells. For translational research, animal models mimicking human disease are crucial, however, most often a compromise between size, cost and features similar to human disease.

PC228. A Magnetic Cannulation Approach Reduces Time and Radiation Exposure During Simulated Fenestrated Endograft Repair

June 1, 2018 - 00:00
The evolution of fenestrated endografts continues to expand endovascular options into challenging pelvic, visceral, and arch regions of the aorta. Enthusiasm of these new endografts is tempered, however, by increased procedural time, and more importantly, significantly increased radiation exposure to operators, staff, and patients. In particular, efficient cannulation of fenestrated endografts with customized branches in a three-dimensional space is limited by two-dimensional fluoroscopic imaging.

PC226. Metabolites Altered in Diabetic Macrophages Influence Chronic Inflammation

June 1, 2018 - 00:00
It has been well-established that type 2 diabetes is a disease associated with chronic, dysregulated systemic inflammation, particularly involving macrophages that constitutively secrete elevated levels of proinflammatory cytokines. Macrophages play a pivotal role in controlling inflammation following injury. Recent evidence suggests that intermediary metabolism alters gene expression, and thus function, in macrophages, providing a molecular link between metabolism and innate immunity. For example, changes in the levels of the metabolite and methyl donor S-adenosyl methionine (SAM) can affect the status of histone methyltransferase enzymes that trimethylate histone 3 at lysine residue 4 (H3K4me3), resulting in increased gene activation.

PC224. Application of a Cryogel-Coated Prosthetic Vascular Graft Material for Delivery of Targeted Gene Therapies in a Rabbit Model

June 1, 2018 - 00:00
The long-term success of prosthetic vascular grafts for revascularization in peripheral arterial disease is limited by the development of anastomotic neointimal hyperplasia (ANIH). We have constructed a bioactive prosthetic graft material (BPGM) by coating polyethylene terephthalate with an antithrombogenic cryogel polymer layer capable of delivering biologic agents to human aortic endothelial cells in vitro. Our goal is to evaluate our hybrid prosthetic graft material in vivo using a rabbit carotid interposition bypass model.

PC222. Duplex Scan and Histologic Assessment of Acute Renal Injury in a Kidney-Kidney Crosstalk Swine Experimental Model

June 1, 2018 - 00:00
The objective of this study was to identify the effect of two left renal vasculature occlusion strategies on the duplex ultrasound-assessed rheology and histology of the contralateral kidney.